More than one way to build a flagellum: comparative genomics of parasitic protozoa
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چکیده
منابع مشابه
More than one way to build a flagellum: comparative genomics of parasitic protozoa
The membrane bound, microtubular axonemes of eukaryotic cilia and flagella are assembled at their distal tips. The discovery of intraflagellar transport (IFT) in Chlamydomonas provided an exciting and seemingly unifying framework for the formation of all eukaryotic cilia and flagella [1–3]. IFT operates in the space between the axoneme and the flagellar membrane to move particles from and to th...
متن کامل[Comparative genomics of trypanosomatid parasitic protozoa].
A comparison of gene content and genome architecture of Trypanosoma brucei, Trypanosoma cruzi, and Leishmania major, three related pathogens with different life cycles and disease pathology, revealed a conserved core proteome of about 6200 genes in large syntenic polycistronic gene clusters. Many species-specific genes, especially large surface antigen families, occur at nonsyntenic chromosome-...
متن کاملMore than one way to go.
D ramatic changes accompany the death of cells. Attempts to align these changes into cognate groups and identify the mechanisms responsible for them have led to substantial and sometimes surprising insights into cell biology. One such constellation of structural and functional changes is associated with apoptosis (a death process found in development, atrophy, the targets of cell killing by the...
متن کاملMore than one way to attach
ow cells connect to each other and to the extracellular matrix (ECM) was a sticky issue in the early 1980s. Integrins, molecules that hook the cy-toskeleton to ECM proteins such as collagen and fibronectin, hadn't been discovered, but evidence for a link between external and internal fibers was mounting. For example, Irwin Singer (1979) observed that extra-cellular fibronectin molecules closely...
متن کاملThere's More than One Way
We hooked the 5th wheel and boat to the truck for the 240-mile drive to Salmon Falls Creek Reservoir for a walleye tournament. The reservoir is between Twin Falls, Idaho and Jackpot, Nevada. We always look forward to fishing this tournament as it’s a good walleye fishery and we have a lot of friends in the area. We pulled into the federal camp ground at the lake at noon on June 10 and were look...
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ژورنال
عنوان ژورنال: Current Biology
سال: 2004
ISSN: 0960-9822
DOI: 10.1016/j.cub.2004.07.041